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Agents that increase GLP-1R signaling also appear to reduce the likelihood of developing diabetic retinopathy, AMD, cognitive dysfunction, motor dysfunction, stroke-induced neurodegenerative impairments, and neuropathy, supporting a potential neuroprotective effect of semaglutide in glaucoma
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![Efficacy of tirzepatide in phase 2 (GPGB; [14]) and phase 3 (SURPASS-1](https://www.researchgate.net/publication/363201315/figure/fig3/AS:11431281082605778@1662084799021/Efficacy-of-tirzepatide-in-phase-2-GPGB-14-and-phase-3-SURPASS-1-to-5-15-19.png)
